To search by structure, left click in the box below to display the chemdraw toolbar. Then, draw the chemical structure of interest in the box using the toolbar. When your structure is complete, click “Search by Name” or “Search by SMILES” to generate the product name or SMILES respectively. This feature will search within the Gelest product database for matching chemical names or SMILES. Note: In cases where Gelest uses alternate chemical names, it may be necessary to search for the product of interest by its CAS#.
All structures are computer generated. Please rely on the product data below for placing your order. If you see any errors in structures, please email customer service so that they can be addressed.
Phenyl-Containing Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
Tri-substituted Silane Reducing Agent
Organosilanes are hydrocarbon-like and possess the ability to serve as both ionic and free-radical reducing agents. These reagents and their reaction by-products are safer and more easily handled and disposed than many other reducing agents. The metallic nature of silicon and its low electronegativity relative to hydrogen lead to polarization of the Si-H bond yielding a hydridic hydrogen and a milder reducing agent compared to aluminum-, boron-, and other metal-based hydrides. A summary of some key silane reductions are presented in Table 1 of the Silicon-Based Reducing Agents brochure.
Boiling Point: 156-7°
EINECS Number: 212-170-5
Melting Point: -124°
Molecular Weight: 136.27
Alternative Name: DIMETHYLPHENYLSILANE
Specific Gravity: 0.889
Flashpoint: 38°C (100°F)
HMIS Key: 2-2-1-X
Hydrolytic Sensitivity: 3: reacts with aqueous base
Refractive Index: 1.4995
Application: Review of synthetic utility.1
Used to prepare ?-phenyldimethylsilyl esters with high enantioselectivity.2
Yields optically active reduction products with chiral Rh or Pd catalysts.3
Undergoes 1,4-addition to pyridines forming N-silylated dihydropyridines.4
Hydrosilylation of 1,4-bis(trimethylsilyl)butadiyne can go to the trisilyl allene or the trisilyl enyne.5
Reference: 1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 254-255.
2. Zhang, Y.-Z. et al. Angew. Chem., Int. Ed. Engl. 2008, 47, 8496.
3. F&F: Vol. 12, p 209; Vol. 13, p 123; Vol. 15, p 168.
4. >Gutsulyak, D. V. et al. Angew. Chem., Int. Ed. Engl. 2011, 50, 1384.
5. Kusumoto, T. et al. Bull. Chem. Soc. Jpn. 1992, 65, 1280.
Additional Properties: Vapor pressure, 25°: 4 mm