TRIMETHYLSILANE

Product Code: SIT8570.0
CAS No: 993-07-7
SDS Sheets: EU | US
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993-07-7
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100 g
$420.00
1 kg
$2,256.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • Einecs Number

    213-603-0
  • Synonyms

    3MS
  • HMIS

    2-4-1-X
  • Molecular Formula

    C3H10Si
  • Molecular Weight (g/mol)

    74.2
  • TSCA

    Yes
  • Delta H Vaporization (kJ/mol)

    5.8 kcal/mole
  • Autoignition Temp (˚C)

    320
  • Boiling Point (˚C/mmHg)

    6.7
  • Density (g/mL)

    0.638
  • Density Temperature (˚C)

    6.7
  • Melting Point (˚C)

    -135.9°

Additional Properties

  • Hydrolytic Sensitivity

    3: reacts with aqueous base

    • Application

    Employed in plasma treatment of surfaces.1
    Treatment of titanium alloys and stainless steel surfaces inhibits biofilm formation.2

    Fieser

    F&F: Vol. 1, p 1235; Vol. 2, p 441; Vol. 13, p 101; Vol. 16, p 292.

    Reference

    1. Hendricks, N. et al. Semiconductor Int'l. 2000, 23, 95.
    2. Ma, Y. et al. Antimicrob. Agents Chemother. 2012, 56, 5923.

    Safety

  • Hazard Info

    ihl rat, LC50: >5,000 ppm/1H
  • Packaging Under

    Helium

    • Tri-substituted Silane Reducing Agent

    Organosilanes are hydrocarbon-like and possess the ability to serve as both ionic and free-radical reducing agents. These reagents and their reaction by-products are safer and more easily handled and disposed than many other reducing agents. The metallic nature of silicon and its low electronegativity relative to hydrogen lead to polarization of the Si-H bond yielding a hydridic hydrogen and a milder reducing agent compared to aluminum-, boron-, and other metal-based hydrides. A summary of some key silane reductions are presented in Table 1 of the Silicon-Based Reducing Agents brochure.

    Trimethylsilane, 3MS; 2-Methyl-2-silapropane; Trimethylsilylhydride

  • ΔHcomb: -3,206 kJ/mol
  • ΔHform: -163 kJ/mol
  • ΔHvap: 24.3 kJ/mol
  • Dipole moment: 0.52 debye
  • Vapor pressure, 25 °C: 1,218 mm
  • Critical temperature: 158.85 °C
  • Critical pressure: 31.48 atm
  • Potential reducing agent that will produce low boiling hexamethyldisiloxane by-product
  • Extensive review of silicon based reducing agents: Larson, G.; Fry, J. L. "Ionic and Organometallic-Catalyzed Organosilane Reductions", Wipf, P., Ed.; Wiley, 2007

    • Silicon Chemistry, Articles

    Key Organosilane Reductions – Larson

    The Si-H bond, based on the relative electrongativities of Si and H, is polarised such that the hydrogen is slightly hydridic in nature. The fact that the silanes are not strongly hydridic makes them excellent candidates for mild and selective reductions of organic functional groups.

    Silicon Chemistry, Articles

    Organosilane Reductions with Polymethylhydrosiloxanes – Larson

    The reduction of a comprehensive range of organic functional groups ranging from carboxylic acids to aryl fluorides have been shown to be possible with a variety of organosilanes. A comprehensive review of the ionic and transition metal-catalyzed reductions of organic functional groups has recently appeared.

    Silicon Chemistry, Articles

    Tetramethyldisiloxane: A Practical Organosilane Reducing Agent – Larson

    Silicon Chemistry, Articles

    The Synthesis of Gliflozins – Larson

    Some of the general approaches to the key steps in the synthesis of gliflozins, a class of glucose transporters, are discussed. In particular the glycosidation step for the introduction of the key aryl moiety onto the glucose and the reduction steps are presented.  Click here for more product information on tetramethyldisiloxane (TMDO, TMDS) reducing agent.

    Silicon Chemistry, Applied Technology

    Understanding ALD MLD and SAMs as they enter the fab – Arkles, Goff, & Kaloyeros