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Product Code: SIT7906.0

Cas No: 67373-56-2

R&D quantities:

25 g

Interested in a Commercial Order?

Boiling Point: 55-6° / 10

Melting Point: 14-15°

Molecular Weight: 178.78


Specific Gravity: 0.911

Flashpoint: 51°C (124°F)

HMIS Key: 3-2-1-X

Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents

Formula: C8H19ClSi

Refractive Index: 1.4490

Application: Review of synthetic utility.1
The N-silylated ?-lactam shows increased hydrolytic stability over that of the analogous N-TBS derivative.2

Reference: 1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 263-265.
2. Wetter, H.; Oertle, K. Tetrahedron Lett. 1985, 26, 5515.

Fieser: F&F: Vol. 13, p 74.