t-BUTYLDIMETHYLCHLOROSILANE, 2.85M in toluene, 48-52% solution

Product Code: SIB1935.5
CAS No: 18162-48-6
SDS Sheets: EU | US
COMMERCIAL
18162-48-6
Pack Size
Quantity
Price
 
100 g
$83.00
750 g
$218.00
2 kg
$400.00
15 kg
Contact Us For Pricing
160 kg
Contact Us For Pricing

Product data and descriptions listed are typical values, not intended to be used as specification.

  • Einecs Number

    242-042-4
  • HMIS

    3-4-1-X
  • Molecular Formula

    C6H15ClSi
  • Molecular Weight (g/mol)

    150.72
  • TSCA

    Yes
  • Boiling Point (˚C/mmHg)

    NA
  • Density (g/mL)

    0.866
  • Flash Point (˚C)

    4
  • Refractive Index @ 20˚C

    1.460

Additional Properties

  • Hydrolytic Sensitivity

    7: reacts slowly with moisture/water
  • Safety

  • Packaging Under

    Nitrogen
  • Trialkylsilyl Blocking Agent

    Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.

    tert-Butyldimethylchlorosilane; TBS-Cl; Chlorodimethyl-t-butylsilane; tert-Butylchlorodimethylsilane; Chloro(1,1-dimethylethyl)dimethylsilane

  • 2.85M in toluene
  • Used for the protection of alcohols, amines, thiols, lactams, and carboxylic acids
  • Clean NMR characteristics of protecting group
  • Facile removal with flouride ion sources
  • Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure