Product Code: SIT8606.3
CAS No: 2975-46-4
SDS Sheets: EU | US
Pack Size
2 kg
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Product data and descriptions listed are typical values, not intended to be used as specification.

  • HMIS

  • Molecular Formula

  • Molecular Weight (g/mol)

  • Purity (%)

  • TSCA

  • Boiling Point (˚C/mmHg)

  • Density (g/mL)

  • Flash Point (˚C)

    >25 °C
  • Refractive Index @ 20˚C


Additional Properties

  • Hydrolytic Sensitivity

    4: no reaction with water under neutral conditions
  • Application

    Used in the preparation of 1,3,5-triynes.1


    1. Mukai, C. et al. J. Org. Chem. 2001, 66, 5875.


  • Packaging Under

  • Alkynylsilane Cross-Coupling Agent

    The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

    3-Trimethylsilylpropynal; 3-Trimethylsilyl-2-propyn-1-al; 3-(Trimethylsilyl)propargyl aldehyde; Trimethylsilyl)acetylenecarboxaldehyde

  • Potential for the formation of alkynyl aldehydes
  • Used in the preparation of 1,3,5-triynes
  • Potential for the synthesis of 3-subsubstituted alkynals
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Silicon Chemistry, Articles

    Silicon-Based Formation of Carbon-Carbon Bonds – Larson

    Hatanaka and Hiyama first reported the palladium-catalyzed, fluoride-promoted reaction of aryl, alkenyl, allyl, and ethynyltrimethylsilanes with aryl, vinil and allyl halides to form the respective cross-coupled products


    Some Aspects of the Chemistry of Alkynylsilanes – Larson

    In amongst the considerable chemistry of acetylenes there lies some unique chemistry of alkynylsilanes (silylacetylenes) some of which is reviewed herein. This unique character is exemplified not only in the silyl protection of the terminal C–H of acetylenes, but also in the ability of the silyl group to be converted into other functionalities after reaction of the alkynylsilane and to its ability to dictate and improve the regioselectivity of reactions at the triple bond. This, when combined with the possible subsequent transformations of the silyl group, makes their chemistry highly versatile and useful.