Additional Properties
- HMIS 3-4-1-X
- Molecular Formula C6H18LiNSi2
- Molecular Weight (g/mol) 167.33
- TSCA Yes
- Boiling Point (˚C/mmHg) NA
- Density (g/mL) 0.716
- Flash Point (˚C) -23 °C
Application
Review of synthetic utility.1
Used in the use of chloroform in the trichloromethylation of a ketone in a scaled-up synthesis of ?-secretase inhibitor, spiropiperidine.2
Reference
1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 356-367.
2. Henegar, K. E. et al. Org. Process. Res. Dev. 2013, 17, 985.
Safety