Additional Properties
- Einecs Number 224-123-6
- HMIS 2-3-0-X
- Molecular Formula C4H11ISi
- Molecular Weight (g/mol) 214.12
- Purity (%) 97%
- TSCA Yes (L)Low Volume Exemption
- Boiling Point (˚C/mmHg) 140-142
- Density (g/mL) 1.441
- Flash Point (˚C) 31 °C
- Refractive Index @ 20˚C 1.4910
Application
Review of synthetic utility.1
Employed in silyl-methylation of alkynes.2
Converts aldehydes, ketones, ?,?-enones to silyl enol ethers.3
Intermediate for allylic silane synthon, 2-(trimethylsilyl)ethyltriphenylphosphonium iodide.4
Useful for the introduction of the trimethylsilylmethyl group.5
Reference
1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 323-336.
2. Schmid, R. et al. J. Am. Chem. Soc. 1980, 102, 5122.
3. Cazeau, P. et al. Tetrahedron 1987, 43, 2075, 2089.
4. Fleming, I. et al. Synthesis 1979, 446.
5. Vedejs, E. J. Org. Chem. 1985, 50, 2170.
Safety
