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Product Code: SID3603.0

Cas No: 3550-35-4

50 g
Trialkylsilyl Blocking Agent

Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.

N,N-Dimethylaminotriethylsilane; Triethylsilyldimethylamine
  • Very reactive triethylsilyl protecting group
  • Dimethylamine by-product produced
  • Used primarily for the protection of alcohols
  • Can be used to protect amines and carboxylic acids
  • Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure
  • Specific Gravity: 0.8044

    Flashpoint: 26°C (79°F)

    HMIS Key: 3-3-1-X

    Hydrolytic Sensitivity: 7: reacts slowly with moisture/water

    Formula: C8H21NSi

    Refractive Index: 1.4325