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Product Code: SID3345.0

Cas No: 85272-31-7

R&D quantities:

2.5 kg
25 g
5 g

Boiling Point: 73-5° / .35

Molecular Weight: 440.46

Specific Gravity: 1.358

Flashpoint: 90°C (194°F)

HMIS Key: 3-2-1-X

Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents

Formula: C10H18F6O6S2Si

Refractive Index: 1.3975

Application: Review of synthetic utility.1
Reagent for protection of diols.2
Used to doubly block sialic acid for use in efficient silylation reactions.3
Can protect diols and be regioselectively mono-deprotected.4

Reference: 1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 209-222.
2. Corey, E. J.; Hopkins, P. B. Tetrahedron Lett. 1982, 23, 4871.
3. Hanshima, S. Eur. J. Org. Chem. 2009, 4215.
4. Yu, M.; Pagenkopf, B. L. J. Org. Chem. 2002, 67, 4553.