78592-82-2

All structures are computer generated. Please rely on the product data below for placing your order. If you see any errors in structures, please email customer service so that they can be addressed.

4-(t-BUTYLDIMETHYLSILOXY)BUTYNE

Product Code: SIB1939.5

Cas No: 78592-82-2

10 g
$97.00
Alkynylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

4-(t-Butyldimethylsiloxy)butyne; 4-(t-Butyldimethylsiloxy)-1-butyne
  • Protected butynol
  • Potential for the synthesis of silyl-protected butynol derivatives
  • Potential for the formation of TBS-protected butynols
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Specific Gravity: 0.893

    Flashpoint: 58°C (136°F)

    HMIS Key: 2-3-1-X

    Hydrolytic Sensitivity: 7: reacts slowly with moisture/water

    Formula: C10H20OSi

    Refractive Index: 1.4300

    Application: Potential for the synthesis of silyl-protected butynol derivatives.1

    Reference: 1. Larson, G. L. “Silicon-Based Cross-Coupling Reagents” Gelest, Inc. 2011.

    Additional Properties: Protected butynol