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Product Code: SIB1939.5

Cas No: 78592-82-2

10 g
Alkynylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

4-(t-Butyldimethylsiloxy)butyne; 4-(t-Butyldimethylsiloxy)-1-butyne
  • Protected butynol
  • Potential for the synthesis of silyl-protected butynol derivatives
  • Potential for the formation of TBS-protected butynols
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Specific Gravity: 0.893

    Flashpoint: 58°C (136°F)

    HMIS Key: 2-3-1-X

    Hydrolytic Sensitivity: 7: reacts slowly with moisture/water

    Formula: C10H20OSi

    Refractive Index: 1.4300

    Application: Potential for the synthesis of silyl-protected butynol derivatives.1

    Reference: 1. Larson, G. L. “Silicon-Based Cross-Coupling Reagents” Gelest, Inc. 2011.

    Additional Properties: Protected butynol