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Product Code: SIT8623.0

Cas No: 97927-35-0

2.5 g

Product data and descriptions listed are typical values, not intended to be used as specification.

Alkynylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

Trimethylsilyl (trimethylsilyl)propynoate; 2,2,2-Trimethyl-2-silapentynoic acid trimethylsilyl ester
  • Potential for the synthesis of 3-substituted propiolic acid derivatives
  • Potential for the formation of propiolic acid derivatives
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Flashpoint: 43°C (109°F)

    HMIS Key: 3-2-1-X

    Hydrolytic Sensitivity: 7: reacts slowly with moisture/water

    Formula: C9H18O2Si2

    Refractive Index: 1.4400

    Application: Potential for the synthesis of 3-substituted propiolic acid derivatives.1

    Reference: 1. Larson, G. L. “Silicon-Based Cross-Coupling Reagents” Gelest, Inc. 2011