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- Synonyms DONDONI REAGENT
- HMIS 2-3-1-X
- Molecular Formula C6H11NSSi
- Molecular Weight (g/mol) 157.31
- Boiling Point (˚C/mmHg) 51-3° / 10
- Density (g/mL) 0.986
- Flash Point (˚C) 62°C (144°F)
- Refractive Index @ 20˚C 1.498
Review of synthetic utility.1
Convenient substitute for 2-lithiothiazole for introducing various substituents at C-2 of the thiazole ring.2
F&F: Vol. 16, p 362.
1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 712-719.
2. Dondoni, A. et al. J. Org. Chem. 1988, 53, 1748.