2-TRIMETHYLSILYLTHIAZOLE

Product Code: SIT8612.0
CAS No: 79265-30-8
SDS Sheets: EU | US
Pack Size
Quantity
Price
 
5 g
$248.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • Synonyms

    DONDONI REAGENT
  • HMIS

    2-3-1-X
  • Molecular Formula

    C6H11NSSi
  • Molecular Weight (g/mol)

    157.31
  • Boiling Point (˚C/mmHg)

    51-3° / 10
  • Density (g/mL)

    0.986
  • Flash Point (˚C)

    62°C (144°F)
  • Refractive Index @ 20˚C

    1.498

Additional Properties

  • Hydrolytic Sensitivity

    7: reacts slowly with moisture/water
  • Application

    Review of synthetic utility.1
    Convenient substitute for 2-lithiothiazole for introducing various substituents at C-2 of the thiazole ring.2

    Fieser

    F&F: Vol. 16, p 362.

    Reference

    1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 712-719.
    2. Dondoni, A. et al. J. Org. Chem. 1988, 53, 1748.

    Safety

  • Packaging Under

    Nitrogen