5683-31-8

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3-TRIMETHYLSILYLPROPYNOIC ACID

Product Code: SIT8606.6

Cas No: 5683-31-8

R&D quantities:

5 g
$237.00

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Alkynylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

3-Trimethylsilylpropynoic acid; 2,2,-Dimethyl-2-silapentynoic acid; 3-(Trimethylsilyl)-2-propynoic acid
  • Potential for the preparation of propiolic acid derivatives
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Boiling Point: 105-9° / 10

    Melting Point: 47-9°

    Molecular Weight: 142.23

    Flashpoint: 96°C (205°F)

    HMIS Key: 3-1-1-X

    Hydrolytic Sensitivity: 4: no reaction with water under neutral conditions

    Formula: C6H10O2Si

    Application: Potential for the preparation of propiolic acid derivatives.1

    Reference: 1. Larson, G. L. “Silicon-Based Cross-Coupling Reagents” Gelest, Inc. 2011.