2-TRIMETHYLSILYL-1,3-DITHIANE

Review of synthetic utility.¹
Employed in synthesis of acylsilanes.²
With BrF3 converts the oxygen of aldehydes and ketones to difluoromethyl groups.³
Used in the preparation of acylsilanes.⁴
Used in the preparation of unsaturated dithioketene acetals in a Peterson reaction.⁵
Important reagent for Type I Anion Relay Chemistry (ARC).⁶

F&F: Vol. 4, p 284; Vol. 10, p 380.

1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 604-609.
2. Corey, E. J. et al. J. Am. Chem. Soc. 1967, 89, 434.
3. Cohen, O. et al. Tetrahedron 2009, 65, 1361.
4. Brinkmeyer, R. S. Tetrahedron Lett. 1979, 20, 207.
5. Carey, F. A.; Court, A. S. J. Org. Chem. 1972, 37, 4474.
6. Smith, A. B., III; Wuest, W. M. Chem. Commun. 2008, 5883.