1-(TRIMETHYLSILOXY)-1,3-BUTADIENE

Product Code: SIT8571.0
CAS No: 6651-43-0
SDS Sheets: EU | US
Pack Size
Quantity
Price
 
25 g
$262.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • HMIS

    2-3-1-X
  • Molecular Formula

    C7H14OSi
  • Molecular Weight (g/mol)

    142.27
  • Boiling Point (˚C/mmHg)

    131°
  • Density (g/mL)

    0.811
  • Flash Point (˚C)

    25°C (77°F)
  • Refractive Index @ 20˚C

    1.4480

Additional Properties

  • Hydrolytic Sensitivity

    7: reacts slowly with moisture/water
  • Application

    Review of synthetic utility.1
    Reacts with phenylsulfenyl chlorides at ?-position.2
    Used in efficient enantioselective synthesis of tamiflu.3
    Undergoes Diels-Alder reactions with high stereoselectivity.4

    Reference

    1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 677-680.
    2. Fleming, I. et al. Tetrahedron Lett. 1979, 20, 3205.
    3. Yamatsugu, K. et al. Angew. Chem., Int. Ed. Engl. 2009, 48, 1070.
    4. Rigby, J. H.; Kierkus, P. C. J. Am. Chem. Soc. 1989, 111, 4125.

    Safety

  • Packaging Under

    Nitrogen