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Product Code: SIT8343.0

Cas No: 53883-59-3

R&D quantities:

2.5 g

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Arylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

m-(Trifluoromethyl)phenyltrimethoxysilane; 1-Trimethoxysilyl-4-trifluoromethylbenzene; 1-Trifluoromethyl-4-(trimethoxysilyl)benzene
  • Useful for introduction of m-trifluoromethylphenyl group
  • Cross-coupling reagent
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Boiling Point: 102-105° / 15

    Molecular Weight: 266.29

    Specific Gravity: 1.20

    HMIS Key: 3-2-1-X

    Hydrolytic Sensitivity: 7: reacts slowly with moisture/water

    Formula: C10H13F3O3Si

    Additional Properties: Cross-coupling reagent