m-(TRIFLUOROMETHYL)PHENYLTRIMETHOXYSILANE

Product Code: SIT8343.0
CAS No: 53883-59-3
SDS Sheets: EU | US
Pack Size
Quantity
Price
 
2.5 g
$348.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • HMIS

    3-2-1-X
  • Molecular Formula

    C10H13F3O3Si
  • Molecular Weight (g/mol)

    266.29
  • TSCA

    No
  • Boiling Point (˚C/mmHg)

    102-105/15
  • Density (g/mL)

    1.20

Additional Properties

  • Hydrolytic Sensitivity

    7: reacts slowly with moisture/water
  • Safety

  • Packaging Under

    Nitrogen
  • Arylsilane Cross-Coupling Agent

    The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

    m-(Trifluoromethyl)phenyltrimethoxysilane; 1-Trimethoxysilyl-4-trifluoromethylbenzene; 1-Trifluoromethyl-4-(trimethoxysilyl)benzene

  • Useful for introduction of m-trifluoromethylphenyl group
  • Cross-coupling reagent
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Silicon Chemistry, Articles

    Silicon-Based Formation of Carbon-Carbon Bonds – Larson

    Hatanaka and Hiyama first reported the palladium-catalyzed, fluoride-promoted reaction of aryl, alkenyl, allyl, and ethynyltrimethylsilanes with aryl, vinil and allyl halides to form the respective cross-coupled products