SODIUM (2-THIENYL)DIMETHYLSILANOLATE, 2M in methyltetrahydrofuran

Product Code: SIS6987.0
CAS No: 879904-87-7
SDS Sheets: EU | US
Pack Size
Quantity
Price
 
10 g
$290.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • HMIS

    2-4-1-X
  • Molecular Formula

    C6H9NaOSSi
  • Molecular Weight (g/mol)

    180.31
  • TSCA

    No
  • Boiling Point (˚C/mmHg)

    NA
  • Density (g/mL)

    0.961
  • Flash Point (˚C)

    -14 °C

Additional Properties

  • Hydrolytic Sensitivity

    5: forms reversible hydrate
  • Application

    Sodium silanolate generated "in-situ".1

    Reference

    1. Denmark, S. E.; Baird, J. D. Org. Lett. 2006, 8, 793.

    Safety

  • Packaging Under

    Nitrogen
  • Arylsilane Cross-Coupling Agent

    The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

    Sodium (4-methylphenyl)dimethylsilanolate

  • Sodium silanolate generated “in-situ”
  • 2 M in Tetrahydrofuran
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Silicon Chemistry, Articles

    Silicon-Based Formation of Carbon-Carbon Bonds – Larson

    Hatanaka and Hiyama first reported the palladium-catalyzed, fluoride-promoted reaction of aryl, alkenyl, allyl, and ethynyltrimethylsilanes with aryl, vinil and allyl halides to form the respective cross-coupled products