118722-54-6

All structures are computer generated. Please rely on the product data below for placing your order. If you see any errors in structures, please email customer service so that they can be addressed.

(2-PYRIDYL)ALLYLDIMETHYLSILANE, 90%

Product Code: SIP6923.0

Cas No: 118722-54-6

2.5 g
$253.00
Save for Later
Arylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

(2-Pyridyl)allyldimethylsilane; (2-Allyldimethylsilyl)pyridine
  • Water and air-stable arylsilane for formation of 2-aryl pyridines
  • Allylates aldehydes, ketones and imines
  • Allylates ketones and aldehydes in the absence of palladium catalysis
  • Source for other 2- pyridyl allylsilanes
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011

    • Flashpoint: 71°C (160F)

    HMIS Key: 3-2-1-X

    Hydrolytic Sensitivity: 4: no reaction with water under neutral conditions

    Formula: C10H15NSi

    Purity: 90%

    Refractive Index: 1.5046

    Application: Allylates ketones and aldehydes in the absence of palladium catalysis. Source for other 2- pyridyl allylsilanes.1
    Extensive review on the use in silicon-based cross-coupling reactions.2

    Reference: 1. Kamei, T. et al. Org. Lett. 2005, 7, 4725.
    2. Denmark, S. E. et al. Organic Reactions, Vol. 75, Denmark, S. E. ed., John Wiley and Sons, 233, 2011.