368-47-8

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PHENYLTRIFLUOROSILANE, 95%

Product Code: SIP6821.5

Cas No: 368-47-8

R&D quantities:

50 g
$182.00
Arylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

Phenyltrifluorosilane; Trifluorophenylsilane
  • Dipole moment: 2.77 debye
  • Catalyzes the reaction of trimethylsilylmethyl imidates with dipolarophiles
  • Cross-couples with aryl and vinyl triflates
  • Couples with aryl bromides in presence of fluoride
  • Couples with 2° alkyl bromides and iodides
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Boiling Point: 101-2°

    Melting Point: -19°

    Molecular Weight: 162.19

    Specific Gravity: 1.2169

    Flashpoint: -5°C (23°F)

    HMIS Key: 3-4-1-X

    Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents

    Formula: C6H5F3Si

    Purity: 95%

    Refractive Index: 1.4110

    Application: Catalyzes the reaction of trimethylsilylmethyl imidates with dipolarophiles.1

    Reference: 1. Washizuka, K. et al. Tetrahedron 1999, 55, 12969.

    Fieser:

    Additional Properties: Dipole moment: 2.77 debye