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Product Code: SIP6716.1

Cas No: 20082-71-7

5 g

Product data and descriptions listed are typical values, not intended to be used as specification.

Specialty Silicon-Based Blocking Agent

Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.

Pentafluorophenyldimethylchlorosilane; Flophemsylchloride; Flophemsyldimethylchlorosilane; Chlorodimethylpentafluorophenylsilane
  • Ethers detectable at femtogram level by ECD
  • Forms excellent derivatives for mass spectral analysis
  • Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure
  • EINECS Number: 243-506-9

    Alternative Name: FLOPHEMESYL CHLORIDE

    Specific Gravity: 1.367

    Flashpoint: 95°C (203°F)

    HMIS Key: 3-2-1-X

    Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents

    Formula: C8H6ClF5Si


    Refractive Index: 1.4470

    Additional Properties: Derivatizing agent for electron capture detection (ECD)