p-METHOXYPHENYLTRIMETHOXYSILANE

Product Code: SIM6492.55
CAS No: 35692-27-4
SDS Sheets: EU | US
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35692-27-4
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Pack Size
Quantity
Price
 
5 g
$87.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • HMIS

    3-2-1-X
  • Molecular Formula

    C10H16O4Si
  • Molecular Weight (g/mol)

    228.32
  • Purity (%)

    95%
  • TSCA

    No
  • Boiling Point (˚C/mmHg)

    85-90° / 0.15
  • Density (g/mL)

    1.094
  • Density Temperature (˚C)

    25
  • Refractive Index @ 20˚C

    1.4868

Additional Properties

  • Hydrolytic Sensitivity

    7: reacts slowly with moisture/water

    • Safety

  • Packaging Under

    Nitrogen

    • Arylsilane Cross-Coupling Agent

    The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

    p-Methoxyphenyltrimethoxysilane; 4-Trimethoxysilylanisole; (p-Anisyl)trimethoxysilane; 4-(Trimethoxysilyl)anisole; 1-Trimethoxysilyl-4-methoxybenzene; 1-Methoxy-4-(trimethoxysilyl)benzene

  • Couples with heterocyclic amines
  • Undergoes asymmetric coupling with α-bromoesters
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011

    • Silicon Chemistry, Articles

    Silicon-Based Formation of Carbon-Carbon Bonds – Larson

    Hatanaka and Hiyama first reported the palladium-catalyzed, fluoride-promoted reaction of aryl, alkenyl, allyl, and ethynyltrimethylsilanes with aryl, vinil and allyl halides to form the respective cross-coupled products