251453-07-3

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1-(4-METHOXYPHENYL)-1-CHLOROSILACYCLOBUTANE

Product Code: SIM6492.3

Cas No: 251453-07-3

R&D quantities:

2.5 g
$187.00
Arylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

1-(4-Methoxyphenyl)-1-chlorosilacyclobutane
  • Example of aryl-substituted silacyclobutane useful for the transfer of an aryl group in cross-coupling applications
  • Underoes Pd-catalyzed cross-coupling with activated aromatic iodides
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011

    • Boiling Point: 100° / 0.1

    Molecular Weight: 212.74

    Specific Gravity: 1.12

    HMIS Key: 3-2-1-X

    Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents

    Refractive Index: 1.528