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Product Code: SIH5848.0

Cas No: 15719-56-9

10 g

Product data and descriptions listed are typical values, not intended to be used as specification.

Alkynylsilane Cross-Coupling Agent

The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

1-Heptynyltrimethylsilane; 1-(Trimethylsilyl)-1-heptyne; 1-Heptynyltrimethylsilane
  • Useful in Sonogashira reactions
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Flashpoint: 42°C (108°F)

    HMIS Key: 2-2-1-X

    Hydrolytic Sensitivity: 4: no reaction with water under neutral conditions

    Formula: C10H20Si

    TSCA: No

    Refractive Index: 1.4344

    Application: Useful in silicon-mediated Sonogashira cross-coupling reactions.1

    Reference: 1. Larson, G. L. “Silicon-Based Cross-Coupling Reagents” Gelest, Inc. 2011.