4071-88-9

All structures are computer generated. Please rely on the product data below for placing your order. If you see any errors in structures, please email customer service so that they can be addressed.

ETHYL (2-TRIMETHYLSILYL)ACETATE

Product Code: SIE4901.6

Cas No: 4071-88-9

R&D quantities:

5gm
$55.00

Interested in a Commercial Order?

Boiling Point: 157-8°

EINECS Number: 223-783-2

Molecular Weight: 160.29

Specific Gravity: 0.876

Flashpoint: 35°C (95°F)

HMIS Key: 2-3-0-X

Hydrolytic Sensitivity: 2: reacts with aqueous acid

Formula: C7H16O2Si

Refractive Index: 1.4149

Application: Review of synthetic utility.1
In combination with LDA converts ketones to ?,?-unsaturated esters.2
Promotes the addition of alkylnitriles to imines.3
Reagent for conversion of carboxylic acids to ?-hydroxyesters.4

Reference: 1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 297-299.
2. Larson, G. L. et al. Synth. Commun. 1999, 20, 1095.
3. Poisson, T. et al. J. Org. Chem. 2009, 74, 3516.
4. Wadhwa, K.; Verkade, J. J. Org. Chem. 2009, 74, 4368.

Fieser: F&F: Vol. 7, p 150; Vol. 11, p 234, p 237.