1314639-85-4

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DI-t-BUTYLISOBUTYLSILANE

Product Code: SID3224.0

Cas No: 1314639-85-4

R&D quantities:

10 g
$248.00
Trialkylsilyl Blocking Agent

Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.

Di-tert-butylisobutylsilane; BIBS-H; Isobutyldi-t-butylsilylhydride
  • Highly sterically-hindered silane for potential dehydrogenative silylation
  • Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure
  • Boiling Point: 65-70° / 5

    Molecular Weight: 200.44

    Specific Gravity: 0.788

    HMIS Key: 2-3-1-X

    Hydrolytic Sensitivity: 2: reacts with aqueous acid

    Refractive Index: 1.4411