Product Code: SIC2572.0
CAS No: 2351-34-0
SDS Sheets: EU | US
Pack Size
5 g
750 g

Prices listed are EXW price (Morrisville, PA US) in USD. Prices vary depending on currency and Incoterms.

Product data and descriptions listed are typical values, not intended to be used as specification.

  • HMIS

  • Molecular Formula

  • Molecular Weight (g/mol)

  • Purity (%)

  • TSCA

  • Boiling Point (˚C/mmHg)

  • Density (g/mL)

  • Flash Point (˚C)

    2 °C
  • Refractive Index @ 20˚C


Additional Properties

  • Hydrolytic Sensitivity

    8: reacts rapidly with moisture, water, protic solvents
  • Application

    Review of synthetic utility.1
    !ntermediate for enoxysilacyclobutanes.2
    Precursor to various aryl and alkenylsilacyclobutanes suitable as a nucleophile in silicon-based cross-coupling.3


    1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 166-170.
    2. Denmark, S. et al. J. Am. Chem. Soc. 1994, 116, 7026.
    3. Denmark, S. E.; Sweis, R. F. Acc. Chem. Res. 2002, 35, 835.


  • Packaging Under

  • Silane Cross-Coupling Agent

    The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.

    Cyclotrimethylenemethylchlorosilane; 1-Chloro-1-methylsilacyclobutane

  • !ntermediate for enoxysilacyclobutanes
  • Precursor to various aryl and alkenylsilacyclobutanes suitable as a nucleophile in silicon-based cross-coupling
  • Precursor for aryl- and vinyl-substituted silacyclobutanes useful for aryl cross-coupling reactions
  • Extensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011
  • Silicon Chemistry, Articles

    Silicon-Based Formation of Carbon-Carbon Bonds – Larson

    Hatanaka and Hiyama first reported the palladium-catalyzed, fluoride-promoted reaction of aryl, alkenyl, allyl, and ethynyltrimethylsilanes with aryl, vinil and allyl halides to form the respective cross-coupled products