t-BUTYLDIMETHYLSILYLNITRILE

Product Code: SIB1965.0
CAS No: 56522-24-8
Pack Size
Quantity
Price
 
10 g
$183.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • Synonyms

    t-BUTYLDIMETHYLSILYLCYANIDE
  • HMIS

    4-2-1-X
  • Molecular Formula

    C7H15NSi
  • Molecular Weight (g/mol)

    141.29
  • TSCA

    No
  • Boiling Point (˚C/mmHg)

    163-165
  • Flash Point (˚C)

    45 °C
  • Melting Point (˚C)

    76-8°

Additional Properties

  • Hydrolytic Sensitivity

    8: reacts rapidly with moisture, water, protic solvents
  • Application

    Review of synthetic utility.1
    Opens epoxides yielding t-butyldimethylsilyl protected ?-isonitrile alcohols.2
    Forms TBS-protected cyanohydrins in good yields.3

    Reference

    1. Handbook of Reagents for Organic Synthesis, Reagents for Silicon-Mediated Organic Synthesis, Fuchs, P. L. Ed., John Wiley and Sons, Ltd., 2011, p. 120.
    2. Gassman, P. et al. J. Org. Chem. 1986, 51, 5010.
    3. Golinski, M. et al. J. Org. Chem. 1993, 58, 159.

    Safety

  • Packaging Under

    Nitrogen