1-(t-BUTYLDIMETHYLSILYL)IMIDAZOLE

Product Code: SIB1964.0
CAS No: 54925-64-3
SDS Sheets: EU | US
Pack Size
Quantity
Price
 
1 g
$106.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • Einecs Number

    259-398-1
  • HMIS

    2-1-1-X
  • Molecular Formula

    C9H18N2Si
  • Molecular Weight (g/mol)

    182.34
  • Purity (%)

    97%
  • TSCA

    No
  • Boiling Point (˚C/mmHg)

    53° / 0.2
  • Density (g/mL)

    0.939
  • Flash Point (˚C)

    99 °C
  • Refractive Index @ 20˚C

    1.4800

Additional Properties

  • Hydrolytic Sensitivity

    7: reacts slowly with moisture/water
  • Safety

  • Packaging Under

    Nitrogen
  • Trialkylsilyl Blocking Agent

    Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.

    tert-Butyldimethylsilylimidazole; N-(t-butyldimethylsilyl)imidazole

  • Reactive sterically hindered orgaosilane
  • Used for the protection of alcohols, amines, thiols, lactams, and carboxylic acids
  • Clean NMR characteristics of protecting group
  • Facile removal with flouride ion sources
  • Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure