ALLYLTRIISOPROPYLSILANE

Product Code: SIA0535.0
CAS No: 24400-84-8
SDS Sheets: EU | US
Pack Size
Quantity
Price
 
5 g
$206.00

Product data and descriptions listed are typical values, not intended to be used as specification.

  • HMIS

    2-2-0-X
  • Molecular Formula

    C12H26Si
  • Molecular Weight (g/mol)

    198.43
  • Purity (%)

    97%
  • TSCA

    No
  • Boiling Point (˚C/mmHg)

    130° / 16
  • Density (g/mL)

    0.824
  • Flash Point (˚C)

    76 °C
  • Refractive Index @ 20˚C

    1.4670

Additional Properties

  • Hydrolytic Sensitivity

    4: no reaction with water under neutral conditions
  • Application

    Alkylated by primary alkyl bromides with greater regiospecificity than allyltrimethylsilane.1

    Reference

    1. Muchowski, J. et al. Tetrahedron Lett. 1985, 26, 5375.

    Safety

  • Packaging Under

    Nitrogen
  • Trialkylsilyl Blocking Agent

    Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.

    Allyltriisopropylsilane; Propenyltriisopropylsilane; 3-Triisopropylsilylpropene

  • Reaction with triflic acid and then pyridine gives the active triisopropylsilylating agent, triisopropylsilylpyridinium triflate
  • Summary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure